Antidepressants may lower mortality risk in diabetes patients. Depression and diabetes are the two leading cause of premature death. Now, researchers found that taking some antidepressants may reduce early death risk.
Diabetes is the seventh leading cause of death around the world.
The American Diabetes Association estimates that in the United States, 30.3 million people had diabetes in 2015.
According to the World Health Organization (WHO), depression is the leading cause of disability worldwide.
Diabetes raises the risk of developing depression by two to three times in a person. However, of those with both conditions, only 25–50% receives treatment.
Recently, researchers investigated whether taking antidepressants reduces mortality risk in people with both diabetes and depression. The new research findings now feature in The Journal of Clinical Endocrinology & Metabolism.
“The incidence of major depressive disorder among individuals with diabetes is significantly greater than the general population,” explained Dr. Vincent Chin-Hung Chen. “Diabetes and depression each independently contribute to increasing total mortality.” Chen is from Chiayi Chang Gung Memorial Hospital and Chang Gung University in Puzi, Taiwan.
The team analyzed 53,412 people who had diagnosed with diabetes and depression. They obtained these data from the Taiwan National Health Insurance Research Database. The researchers found that of all participants, 50,532 used antidepressants.
The overall analysis showed that high consumption of norepinephrine-dopamine reuptake inhibitors (NDRIs) each day ) was associated with an 80% decrease risk of early death.
“These data provide further rationale for the screening and treating of depression in persons who have diabetes,” Dr. Vincent Chin-Hung Chen said.